Francis Pringle received his medical degree from the University of Leiden on 14 July 1702. He was licensed to practise on 21 November 1704 and admitted as a Fellow of the Royal College of Physicians of Edinburgh on 1 December that same year. Pringle served as President of the College from 1727 until 1731.

Charles Preston received his undergraduate degree from the University of Reims on 14 July 1696 and his Doctor of Medicine from the University of Aberdeen on 21 June 1699. He was admitted licentiate to the Royal College of Physicians of Edinburgh on 21 November 1704 and admitted socius on 1 December, without examination. Preston was a botanist and served as Edinburgh's Professor of Botany. On 4 October 1705 he was appointed to the committee to 'revise the books and rarities of the College'. On 6 December that same year he became College Secretary and Library Keeper and chaired the Library Committee. Preston died in 1711.

George Mackenzie received his medical degree from Marischal College, Aberdeen on 22 November 1703 and was admitted as a Fellow of the Royal College of Physicians of Edinburgh on 1 December 1704. He was associated with Heriot's Hospital and was appointed first physician to Queen Anne in 1714, though the appointment was not renewed by King George I. Mackenzie's appointment to Heriot's Hospital was secured through Dr Stevensone, who withdrew a 200 claim against the hospital in exchange for Mackenzie's succession. His appointment was later rescinded, and Dr Gilbert Rule, a Fellow and Presbyterian minister, was elected in his place in 1711. Mackenzie responded by publishing a pamphlet criticising the decision.

William Eccles was admitted as a Member of the College sometime during the 1680s. He was later suspended from the College for unknown reasons, returning as a Member on 2 December 1703, when he was elected a Censor. Eccles served as President of the College in 1706 and on 26 September that year delivered a discourse before the College entitled 'De Hydrophobia'. He was appointed on 3 May 1709 to a committee for better regulating the practice of medicine among Fellows. His son James also became a doctor, admitted as a Fellow of the College on 24 March 1719.

William Douglas was admitted as a Fellow of the Royal College of Physicians of Edinburgh sometime during the 1680s. There were fifteen ordinary physicians within the College between 1672 and 1853, and Douglas is included in this list.

Thomas Spence was born in Renfrewshire, the son of Nathaniel Spens, MD, and Mary Milliken, the second daughter of James Milliken, Esquire of Milliken, Renfrewshire. He had three brothers and a sister. Spence was admitted as a Fellow of the Royal College of Physicians of Edinburgh sometime during the 1680s. In 1693 he was appointed Fiscal, or Procurator Fiscal, of the College. Spence was also the first Physician to the Royal Infirmary of Edinburgh.

Robert Hay received his medical degree from the University of Leiden on 4 October 1683. He was admitted as a Fellow of the Royal College of Physicians of Edinburgh sometime after 1685 but before 1693.

Charles Oliphant was one of the first candidates to be examined for admission as a Fellow of the Royal College of Physicians of Edinburgh. Having satisfied the examiners, he was licensed to practise on 9 November 1693 and, by another vote in respect of his qualifications, was admitted as a Member of the College that same day. Within six months of his admission, the College had developed the practice of granting a licence and advancing to fellowship in one sitting. During his career, Oliphant served as Treasurer of the College. In December 1699 he was suspended from his position for failing to produce his accounts. The suspension was lifted on 31 January 1700, when Oliphant vacated his position as Treasurer.

Andrew Melville received his MD from the University of Caen in 1683. He was licensed to practise in 1694 and admitted as a Fellow of the Royal College of Physicians of Edinburgh that same year. In 1695, Melville was among several Fellows suspended for inciting a riot. The suspension lasted for five years and was lifted on 31 January 1704. Melville later studied at the University of Leiden in 1703 and at the University of Glasgow under James Woodrow, professor of divinity. His name is attached to the 'Edinburgh Pharmacopoeia' published in 1722.

Thomas Dalrymple was born circa 1663 in Ochiltree, Ayrshire. He was the son of James Dalrymple, 1st Viscount Stair, and Margaret Ross. He was admitted as a Fellow of the Royal College of Physicians of Edinburgh on 30 July 1694, without examination. Dalrymple served as Physician in Ordinary to the royal household. He died unmarried and was buried in the New Church Aisle, Edinburgh.