Adam Freer received his medical degree from the University of Leiden on 28 July 1687. He was admitted as a Fellow of the Royal College of Physicians of Edinburgh on 7 October 1695. From December 1695 to December 1696 Freer served as Treasurer of the College. He was also among several Fellows appointed in December 1696 to revise the 'Edinburgh Pharmacopoeia'.

Matthew Sinclaire was one of the original twenty-one Fellows of the Royal College of Physicians of Edinburgh when it was incorporated by royal charter on 29 November 1681. His name was written tenth on the charter. Sinclaire received his medical degree from the University of Leiden in 1674. He was not recorded as present at the College until the first election day on 30 November 1682 and therefore did not hold one of the first offices. On 2 June 1684 he delivered a discourse before the College entitled 'De Dissenteria'. From 1694 he was chosen alongside Dundas as one of the physicians for the poor for the ensuing year. Sinclaire was also a member of the committee for the revision of the 'Edinburgh Pharmacopoeia' from 9 March 1697. He was the last survivor of the original twenty-one Fellows and died in 1728.

James Stewart was one of the original twenty-one Fellows of the Royal College of Physicians of Edinburgh when it was incorporated by royal charter on 29 November 1681. His name was written eleventh on the charter. Stewart received his medical degree from the University of Leiden in 1674, at the age of twenty-two, having earlier graduated Master of Arts. In March 1682 he served on a committee tasked with revising the Edinburgh Pharmacopoeia. Stewart died in January 1684, having attended only fifteen meetings of the College.

Alexander Cranstone was one of the original twenty-one Fellows of the Royal College of Physicians of Edinburgh when it was incorporated by royal charter on 29 November 1681. His name was written twelfth on the charter. Cranstone served as Treasurer of the College from 1683 and was appointed Procurator Fiscal in 1684. He was the first Vice-President and Censor of the College in 1694. In 1695 he delivered a discourse before the College on an aphorism of Hippocrates. Cranstone was also elected to the committee for revising the 'Edinburgh Pharmacopoeia' on 9 March 1697. He died in 1699.

John Hutton was one of the original twenty-one Fellows of the Royal College of Physicians of Edinburgh when it was incorporated by royal charter on 29 November 1681. His name was written thirteenth on the charter. Hutton received his medical degree from the University of Padua. He served as the first Treasurer of the College from 1681 but resigned from this post in May 1682, leaving Scotland. Hutton also contributed to the creation of the Edinburgh Pharmacopoeia.

John McGill was one of the original twenty-one Fellows of the Royal College of Physicians of Edinburgh when it was incorporated by royal charter on 29 November 1681. His name was written fourteenth on the charter. In 1682 McGill was appointed to a committee tasked with revising the Edinburgh Pharmacopoeia. On 30 November 1684 he delivered a discourse before the College entitled 'De Chillificatione'.

John Lermonth was one of the original twenty-one Fellows of the Royal College of Physicians of Edinburgh when it was incorporated by royal charter on 29 November 1681. His name was written fifteenth on the charter. Lermonth received his medical degree from the University of Leiden in 1675. He served as a Censor of the College from 1684 and was among ten individuals appointed to a committee for collecting subscriptions and planning the management of the Edinburgh Royal Infirmary. The committee hired a small house for receiving the sick poor and appointed twenty managers to oversee its operation.

William Stevensone was one of the original twenty-one Fellows of the Royal College of Physicians of Edinburgh when it was incorporated by royal charter on 29 November 1681. His name was written sixteenth on the charter. Stevensone served as the second Treasurer of the College, elected in 1682, and became its first Librarian in 1683. He retired from his treasurership to take up the librarian post. Stevensone's name disappears from the College meeting minutes after 1684.

James Halket was one of the original twenty-one Fellows of the Royal College of Physicians of Edinburgh when it was incorporated by royal charter on 29 November 1681. Halket received his medical degree from the University of Leiden in 1675. Within four years of the College's establishment, Halket was appointed by the Edinburgh Town Council to be Professor of Medicine at the University of Edinburgh, alongside Robert Sibbald and Archibald Pitcairne. He also took part in examining the first candidate to receive the degree of MD in 1705.

William Wright was one of the original twenty-one Fellows of the Royal College of Physicians of Edinburgh when it was incorporated by royal charter on 29 November 1681. His name was written eighteenth on the charter. Wright undertook a short period of service in the naval medical service, followed by seventeen years in the army in the West Indies. He later practised privately in Jamaica. Wright was a native of Crieff.

Legacy of Slavery

Wright treated and owned enslaved people. The UCL slave ownership database indicates that at abolition, Wright received compensation for the loss of 33 enslaved people that he either owned directly or in partnership with others. According to the Oxford Dictionary of National Biography 'During these years [1764-1777] he became financially successful by investing the income from his medical practice in slaves and land. In mid-1765 he and Thomas Steel owned four slaves, in 1767 fifteen slaves, by 1771 thirty-three slaves’. Wright’s memoirs were amongst those publications which encouraged racial stereotypes and argued for a medical, and biological, basis to such racism.