William Seller was born in Peterhead, the son of a merchant who died when Seller was young. His mother moved with her children to Edinburgh, where Seller was educated at the High School. He studied classics and philosophy at Edinburgh University before turning to medicine and graduating MD in 1821. Shortly after graduation he opened a boarding house for medical students and ran preparatory classes for examinations.

John Reid was born in Bathgate in 1809. He matriculated at Edinburgh University to study classics and mathematics before transferring to medicine and graduating MD in 1830. Reid became assistant physician at the Edinburgh Infirmary in 1830 and studied in Paris from 1831 to 1832. In 1833 he became assistant to Robert Knox at Surgeons' Hall and later lecturer in physiology at the Edinburgh extramural school. In 1838 he was appointed pathologist to the Edinburgh Infirmary and in 1841 became Professor of Anatomy at the University of St Andrews. He died in St Andrews in 1849.

James Young Simpson was born in Bathgate, Linlithgowshire. He entered Edinburgh University as an arts student in 1825 and began medical studies two years later. In 1831 he became assistant to the director of the Royal Dispensary for the Poor and graduated MD in 1832. After touring medical schools in Europe in 1835, he established an obstetric practice in Edinburgh and accepted the post of house surgeon at the City Lying-In Hospital in 1836. In 1840 he was elected Professor of Midwifery at the University of Edinburgh. In 1847 he introduced chloroform anaesthesia into obstetric practice and published his findings shortly afterwards. In 1850 he became Physician to the Royal Infirmary of Edinburgh and President of the Royal College of Physicians of Edinburgh. He was created a baronet in 1866. In the final year of his life he actively supported women's entry into medical education. Simpson died in 1870.

Henry Atkinson received his MD from the University of Erlangen in 1835 and was elected a Fellow of the College in 1836.

William Reid studied at the University of Edinburgh from 1821 to 1823 and became an apprentice at the Royal College of Surgeons in 1822. He graduated MD in 1824, publishing 'Dissertatio medica inauguralis de nupera febris continuae disciplina'. In 1839 he published 'Elements of the Practice of Medicine', intended as a student textbook, and lectured on the principles and practice of medicine.

William Gregory was born in Edinburgh in 1803, the son of James Gregory, Professor of Medicine at the University of Edinburgh. He graduated in medicine at Edinburgh in 1828 and undertook further study on the continent, including at the University of Giessen. Gregory lectured extramurally in chemistry in Edinburgh and later lectured in Glasgow and Dublin. In 1839 he was appointed Professor of Medicine and Chemistry at King's College, Aberdeen, and in 1844 became Chair of Chemistry at the University of Edinburgh. He died in Edinburgh in 1858.

Edward Duffin Allison graduated MD from the University of Aberdeen on 20 August 1827. In 1826 he published 'Observations on the expediency of instituting a friendly association of the medical profession throughout Scotland', proposing a provident society for medical practitioners and their families. Allison was one of the original committee members of the Medical Provident Institution of Scotland, which operated from 1826 to 1833.

John Thomson began his medical training as an apprentice in 1785 before studying at the universities of Glasgow and Edinburgh. While in Edinburgh he became assistant apothecary at the Royal Infirmary in 1790 and president of the Medical Society from 1791 to 1792. He studied in London under John Hunter and returned to Edinburgh in 1793, becoming a Fellow of the College of Surgeons. In 1800 he was appointed one of the surgeons to the Royal Infirmary and began teaching surgery. In 1804 he was appointed to the new professorship of surgery at the College of Surgeons and in 1806 became Professor of Military Surgery at the University of Edinburgh. He received his MD from King's College, Aberdeen, in 1808. Thomson later helped found the Edinburgh New Town Dispensary in 1815 and was appointed Professor of General Pathology at Edinburgh in 1832. He served as President of the Royal College of Physicians of Edinburgh from 1834 to 1836.

John Price received his MD from the University of Aberdeen in 1821 and was elected a Fellow of the Royal College of Physicians of Edinburgh in 1830.

Robert Lewins studied medicine at the University of Edinburgh from 1809 to 1812 and graduated MD on 3 November 1829. He was elected a Fellow of the Royal College of Physicians of Edinburgh on 2 November 1830. Lewins published several papers, including 'Remarks on the Merits and Present State of Vaccination, Wherein the Objections of the Antivaccinists Are Considered' in 1825.