Sir James Coxe was born in Gorgie in 1811, the son of Robert Coxe. He studied medicine in Edinburgh, Gottingen, Heidelberg and Paris and graduated MD from Edinburgh in 1835 before beginning practice in the city. Coxe was elected a Fellow of the Royal College of Physicians in 1837. In 1855 he was appointed Commissioner in Lunacy for Scotland and his work led directly to the Lunacy Act of 1857, for which he was knighted in 1863. Coxe authored the first fifteen Annual Reports of the Scottish Lunacy Commissioners and published 'Lunacy in its Relations to the State' in 1877. He died in Folkestone on 9 May 1878.

Charles Bell was born in 1805 and received his MD from the University of Glasgow in 1836. He became a Fellow of the College in 1837 and died in 1891.

Edmund Beatty Lockyer received his MD from Jena in 1836 and became a Fellow of the College in 1837.

Martin Barry was born in Hampshire in 1802. He studied medicine in Edinburgh, London, Paris, Erlangen and Berlin before receiving his MD from Edinburgh in 1833. He undertook further study in Heidelberg with a particular focus on microscopy. Barry was elected a Fellow of the Royal Society of London in 1840, taught physiology at St Thomas's Hospital in 1843 and later worked as house surgeon at the Royal Maternity Hospital in Edinburgh. He died in Suffolk in 1855.

John Moir was born in a French fortress at Verdun, the son of a naval surgeon. His parents were taken prisoner during the Napoleonic Wars and returned to Edinburgh in 1814, where his father established a medical practice with a special interest in obstetrics. John Moir graduated MD in 1827, specialised in midwifery and served on the staff of the maternity hospital, teaching students and nurses.

George Paterson received his MD from the University of Edinburgh on 12 July 1833 and was admitted a Fellow of the Royal College of Physicians of Edinburgh on 15 July 1837. He practised chiefly in Edinburgh and for a period in Tiverton, Devon. Paterson served as Physician and Senior Physician to the Royal Infirmary of Edinburgh, lecturer on clinical medicine, Medical Officer to the New Town Dispensary and secretary of the College. In 1862 he was appointed Deputy Commissioner in Lunacy for Scotland and retired from this role in 1877. He died on 18 October 1893.

Patrick Rolland received his MD in 1826 from the University of St Andrews at Kiel. He became a Fellow of the College in 1838 and shortly afterwards planned to settle in South America.

John Home studied medicine at the University of Edinburgh in 1820, 1822 and 1825. He received his MD on 13 July 1829 and became a Fellow of the Royal College of Physicians of Edinburgh on 6 February 1838.

William Henderson was born in Thurso in 1810. He graduated MD at Edinburgh in 1831 and pursued further study in Berlin, Paris and Vienna. In 1832 he was elected physician to the Edinburgh Fever Hospital and later became pathologist at the Royal Infirmary. In 1842 he was appointed Professor of Pathology at the University of Edinburgh. After adopting homeopathic practice he lost his hospital post and much of his private practice. Henderson died in Edinburgh in 1872.

James Marr received his MD from the University of St Andrews on 6 December 1837 and became a Fellow of the Royal College of Physicians of Edinburgh on 6 February 1838. He specialised in midwifery and obstetrics and worked as lecturer, physician to the lying-in hospital and midwifery dispensary, and physician accoucheur to the Royal Dispensary. Marr published papers including 'On the Nature, Mechanism, and Treatment of Face Presentations' in 1842.