Frailty and its quantitative clinical evaluation

Frailty is a progressive physiological decline in multiple organ systems marked by loss of function, loss of physiological reserve and increased vulnerability to disease and death. Frail older adults are vulnerable to poor health outcomes including an increased risk of disability, social isolation and institutionalisation. With the advances in understanding of the physiological underpinnings and clinical measurement of frailty over the past decade, opportunities both to streamline and quantify the clinical measurement and care planning associated with frailty have emerged.