James Ross (1837–1892) was an Aberdeen medical graduate who, after 13 years in rural general practice, mainly in Lancashire, became a pathologist and then physician to the Manchester Royal Infirmary and professor of medicine at Owens College, Manchester. In mid-career he developed a major interest in clinical neurology and became, apart from Byrom Bramwell in Edinburgh, the only contemporary British physician outside London who had widely recognised neurological expertise. Ross made several notable original contributions to neurological knowledge, particularly in relation to aphasia and peripheral neuritis. He wrote the entire contents of the two editions of the massive two-volume A Treatise on the Diseases of the Nervous System (1881 and 1883), which was very favourably reviewed and commercially successful but which, like its author who died at the height of his powers, was soon forgotten once William Gowers’A Manual of Diseases of the Nervous System became available in the late 1880s.