DEP/DUA/1/47/14 (Transcript version)

Edward Crane

(1789)

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No26. Edward Crane at 45.

In case of this pat a distinctly markd & a severe inst of dysp.

And little doubt that patient right in conj as to cause to which attrib abuse viz of Spirit Liquor.

For except sedent life no cause perhaps more freq gives rise to that affect.

And when prod by long contin & freq action of spirits on stom, is perhaps more obstin & danger than from any other cause.

Indeed rarely cureable as cause prod it very commonly still contin to act.

For after being once habit to use of spirits, very diff to lay it aside

And if pat as he alledged has relinq use, is at least, rare inst of forbearance.

But although thus [decided] in opin both with regard to disease & cause inducing it, yet not altog without [doubt] as to morbid affect induced.

And here I think a quest of some diffic whether are to consider it, as chiefly arising from morb. affect of musc fibres of stom or of secret. [there].

For am inclind to think that dysp. may arise from either [illegible] or from both conj.

In this case pain flatul & vomt give presumpt of loss of tone & irrit of muscul fibres of stom.

While at the same time from viscid & acrid fluid disch by vomiting have presumpt of morbid secret.

Whether however suppose it chiefly conseq of one or other have reason to fear that will prove an obst dis.

And this the rather, as ground for appreh that both conj to consid degr.

But on any view of pathol. is chiefy by restor tone that can look for [cure]

For thus alone that can expect to induce alter on state of secret

Is with this intent that have here had recourse to a med which from sensib qualit at least prom to be an excell stomach.

viz Cortex Angusturae

But of this reserve observ till again speak of case