DEP/DUA/1/34/07 (Normalised version)

Isabel Murray

1784

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N^o 24^th January 23^d 1784

Isabel Murray at 59. complains of great difficulty of breathing & a constant sense of tightness & soreness in the lower part of her thorax. She has a frequent & troublesome cough attended with little expectoration. Two or three times every day, she perceives the sense of a ball rising from the duodenum up to the throat, at this time she [stretches] & [yawns] incessantly & she is relieved from the sensation of the ball by a discharge of wind from the mouth. About four o’Clock in the afternoon she perceives the sensation of coldness & creeping in the lower part of the [extremities]

Both these sensations seem to meet in the small of her back & to pass along the spinal marrow into the head. Immediately afterwards, which is about fifteen minutes from the attack, a severe trembling comes on & continues with little intermission till six o’Clock in the morning when it gradually abates in violence & at length ceases, without her perceiving any increase of heat or sweating.

The pain of her back & head are aggravated all the time that the trembling is present. Pulse frequent & small. Belly bound.

The cough & tightness about the breast with the sensation of the ball are of six months [continuance] but she has only been affected with trembling for eight days she never was similarly affected before.

Cap. Pulv. Ipecac Ji. pro Em. nec non Rx Cup Ammon. grXII Mic Pan. ℥ ii. Spt Corn Cerv. G. s. f. mas. divid in pil XXIV cap. Pil. I. om. m. & vesp.