Is the warfarin saga over?

This review is based on a presentation given by Professor Schulman at the RCPE Haematology Symposium on 4 November 2011.Warfarin is the most widely used oral anticoagulant and has been available for more than 65 years. The last decade has brought a host of new orally available anticoagulants with promising features to clinical trials and some have already been approved for limited indications.