Adrenal insufficiency in decompensated cirrhotic patients without infection: prevalence, predictors and impact on mortality

Background Relative adrenal insufficiency (RAI) is common in compensated and decompensated chronic liver disease in the presence of sepsis. This study was performed to find out the prevalence of RAI in decompensated cirrhotic patients presenting with hepatic encephalopathy and variceal bleeding without any evidence of infection.

A case of Berardinelli-Seip syndrome presenting with cirrhosis

Berardinelli-Seip congenital lipodystrophy (BSCL) is a rare autosomal
recessive disorder of generalised lipoatrophy, characterised by the absence of
functioning adipocytes, with lipid being stored in muscles, the liver and the pancreas.
The usual presentation is in adulthood, with manifestations of insulin resistance,
hypertriglyceridaemia and liver steatosis. Cirrhosis as the first presentation of BSCL in
a young adult is rare. We describe a patient with BSCL presenting with cirrhosis. To the