Journal Mobile

KKP Goh, T Subramaniam
Journal Issue: 
Volume 35: Issue 3: 2005




The  diagnosis  of  phaeochromocytoma  requires  both  a  biochemical demonstration of inappropriately increased catecholamine production as well as anatomical localisation of the tumour.  The addition of plasma metanephrine and serum chromogranin A has increased the repertoire of biochemical tests available. Recent  advances  in  functional  imaging  like  MIBG  and  somatostatin  receptor scintigraphy  have  improved  the  diagnostic  yield  in  extra-adrenal, metastatic  and recurrent tumours which may not be easily recognised on conventional imaging. Although  excision  of  the  tumour  remains  the  mainstay  of  treatment,  the importance of good peri-operative control of blood pressure and post-operative follow up care cannot be over-emphasised.  This paper reviews the various tests currently available and their roles in the evaluation of phaeochromocytoma. It also highlights some of the peri-operative issues in the management of this condition