Author(s): G Gogna, N Patel, P BilinskiJournal Issue: Volume 46: Issue 4: 2016 Format Abstract Renal cell carcinoma has previously been associated with hypoglycaemia in the setting of non-islet cell tumours, caused by a paraneoplastic phenomenon relating to the production of insulin-like growth factor type II. We present a case of recurrent clear cell renal cell carcinoma, leading to an insulin-mediated paraneoplastic phenomenon causing severe recurrent hypoglycaemia. Hypoglycaemina was managed successfully using diazoxide therapy, in conjunction with pazopanib and radiotherapy to reduce tumour burden. PDF https://www.rcpe.ac.uk/sites/default/files/jrcpe_46_4_gogna.pdf Journal Keywords: hypoglycaemiainsulin mediatednon-islet cell tumour hypoglycaemiaparaneoplasticrenal cell carcinoma