Journal Mobile

Author(s): 
RA Frake, DC Rubinsztein
Journal Issue: 
Volume 46: Issue 4: 2016

Format

Abstract

On 3 October 2016, Japanese cell biologist Yoshinori Ohsumi was awarded the Nobel Prize in Physiology or Medicine ‘for his discoveries of mechanisms for autophagy’; autophagy being an intracellular degradation pathway that helps maintain cytoplasmic homeostasis. This commentary discusses Ohsumi’s Nobel prize-winning work in context, before explaining the clinical relevance of autophagy.

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